Search results for " Overcoming"

showing 4 items of 4 documents

Characterization of Human γδ T Lymphocytes Infiltrating Primary Malignant Melanomas

2012

T lymphocytes are often induced naturally in melanoma patients and infiltrate tumors. Given that gamma delta T cells mediate antigen-specific killing of tumor cells, we studied the representation and the in vitro cytokine production and cytotoxic activity of tumor infiltrating gamma delta T cells from 74 patients with primary melanoma. We found that gamma delta T cells represent the major lymphocyte population infiltrating melanoma, and both V delta 1(+) and V delta 2(+) cells are involved. The majority of melanoma-infiltrating gamma delta cells showed effector memory and terminally-differentiated phenotypes and, accordingly, polyclonal gamma delta T cell lines obtained from tumor-infiltrat…

MelanomasCytotoxicity ImmunologicMaleRENAL-CELL CARCINOMA OVERCOMING IMMUNOLOGICAL-TOLERANCE METASTATIC MELANOMA TUMOR-CELLS PHASE-I MEVALONATE PATHWAY TARGETING CTLA-4 LYMPH-NODES IMMUNOTHERAPY CANCERAnatomy and PhysiologySkin NeoplasmsTUMOR-CELLSLymphocytemedicine.medical_treatmentT-LymphocytesSettore MED/19 - Chirurgia PlasticaTARGETING CTLA-4Interleukin 21T-Lymphocyte SubsetsImmune PhysiologyMETASTATIC MELANOMACytotoxic T cellIL-2 receptorSkin TumorsMelanomaOVERCOMING IMMUNOLOGICAL-TOLERANCEAged 80 and overMultidisciplinaryT CellsMelanomaMalignant MelanomaQRReceptors Antigen T-Cell gamma-deltaMiddle AgedCANCERPHASE-Imedicine.anatomical_structureCytokinePhenotypeOncologyCytokinesMedicineFemaleResearch ArticleTumor ImmunologyAdultScienceT cellImmune CellsImmunologyMalignant Skin NeoplasmsDermatologyBiologyImmunophenotypingImmune systemLymphocytes Tumor-InfiltratingmedicineHumansIMMUNOTHERAPYBiologyAgedNeoplasm StagingSettore MED/04 - Patologia GeneraleLYMPH-NODESCancers and NeoplasmsImmunologic Subspecialtiesmedicine.diseaseImmune SystemImmunologyOVERCOMING IMMUNOLOGICAL-TOLERANCE; METASTATIC MELANOMA; TUMOR-CELLS; PHASE-I; MEVALONATE PATHWAY; TARGETING CTLA-4; LYMPH-NODES; IMMUNOTHERAPY; CANCERClinical ImmunologyImmunologic MemoryMEVALONATE PATHWAYPLoS ONE
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Metafisica si dice in molti modi. Sulla recente Storia della metafisica a cura di Enrico Berti

2020

Is it possible to recount the history of metaphysics? And what image of metaphysics can emerge from this historyand from the narration of such a history? The recent volume Storia della metafisica, edited by Enrico Berti and at the coreof the analysis of the present essay, helps us to answer these questions,confirming that metaphysics is said in many ways.

Metaphysics History of metaphysics Meta-metaphysics Overcoming FoundationSettore M-FIL/01 - Filosofia Teoretica
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Overcoming Postmodernity? Reconsidering Animal Life from Heidegger to Derrida

2018

In this paper, I would like to approach the question of language as crucial for the difference between human and non-human animals in the scenario cast by contemporary continental philosophy. I would also like to use this and other topics as a chance to take some general considerations on postmodernity into account, the latter intended as the historical condition in which we are supposed to live.

OvercomingDerridaAnimalityPostmodernityAnimality; Postmodernity; Overcoming; Heidegger; DerridaHeideggerSettore M-FIL/06 - Storia Della Filosofia
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Nuove regole di applicazione del diritto UE in sede nazionale?

2022

Two important judgments of the Consiglio di Stato (Italy) allow revisiting general institutions relating to the primacy of EU law and the instruments that guarantee its application in national law. Among others are the direct effect of the directives, the need for a preliminary ruling, and the so-called double preliminary ruling. Finally, the essay highlights some critical issues regarding the limits of the non-application of the law, the overcoming of the res judicata, and the temporary suspension of the ousting effect of a rule of EU law by national courts.

the need for a preliminary rulingthe temporary suspension of the ousting effect of a rule of EU law by national courts.the direct effect of the directivethe overcoming of the res judicataSettore IUS/14 - Diritto dell'Unione Europeathe temporary suspension of the ousting effect of a rule of EU law by national courtsthe direct effect of the directivesthe limits of the non-application of the lawthe so-called double preliminary rulingthe direct effect of the directives; the so-called double preliminary ruling; the need for a preliminary ruling; the limits of the non-application of the law; the overcoming of the res judicata; the temporary suspension of the ousting effect of a rule of EU law by national courts
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